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Ammonia

CASRN 7664-41-7 | DTXSID0023872

Toxicological Review (PDF) (99 pp, 1.0 M)
IRIS Executive Summary (PDF) (10 pp, 309 K)
Supplemental Information on the Toxicological Review of Ammonia (Inhalation)
Status: Development of the ammonia (re)assessment has been suspended .

On this page:

Key IRIS
Values
Assessment
Status
Chemical
Documents
Other EPA
Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 309 K) Last Updated:

Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 309 K) Last Updated: 09/20/2016

System	RfC (mg/m³)	Basis	PoD	Composite UF	Confidence
Respiratory	5 x 10 ^-1	Decreased lung function and respiratory symptoms	NOAEL (ADJ): 4.9 mg/m³	10	Medium

Cancer Assessment

Weight of Evidence for Cancer (PDF) (10 pp, 309 K)
Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 309 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 309 K)

Not assessed under the IRIS Program.

Program Outlook Details

Public Assessment Materials	Date
Problem Formulation Materials/IRIS Assessment Plan	Apr-2018
Suspended	Dec-2018

Note: The ammonia (re)assessment was suspended in Dec-2018, but may be restarted as Agency priorities change.

Chemical Documents

Apr 2019: IRIS Program Outlook April 2019-Suspended/Discontinued Assessment (Other)

Apr 2018: IRIS Assessment Plan for Ammonia and Ammonium Salts Noncancer Oral (Scoping and Problem Formulation Materials, Suspended) (Report)

Sep 2016: IRIS Toxicological Review of Ammonia Noncancer Inhalation (Final Report) (Report)

Jun 2016: IRIS Toxicological Review of Ammonia Noncancer Inhalation (Interagency Science Discussion Draft) (Report)

Aug 2013: IRIS Toxicological Review of Ammonia (Revised External Review Draft) (Report)

Jun 2012: IRIS Toxicological Review of Ammonia (External Review Draft) (Report)

Mar 2012: IRIS Toxicological Review of Ammonia (Interagency Science Consultation Draft) (Report)

Jun 1987: Health Effects Assessment for Ammonia (Report)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.